Peptipedia
BioregulatorPreclinicalAnimal Studies

Cortagen

Also known as Ala-Glu-Asp-Pro, AEDP

A tetrapeptide bioregulator (Ala-Glu-Asp-Pro) derived from cerebral cortex extracts. Studied for neuroprotection, neural differentiation, and cognitive support.

Preclinical research; approved in Russia as supplement
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Regulatory Pathway

Preclinical
Phase I
Phase II
Phase III
Phase IV
Approved

Dosing Protocol

Typical Dose

10-20 mg daily

Frequency

Once or twice daily

Duration

10-30 day cycles

Community-reported dosing. Individual results vary. Not a medical recommendation.
Typical community protocol: 10-20 mg daily via Oral capsules or sublingual, Once or twice daily. Dose range: 10-20 mg daily. Duration: 10-30 day cycles.

Timing & Administration

Administer via Oral capsules or sublingual. Frequency: Once or twice daily.

Mechanism of Action

Regulates neurotrophic signaling, gene transcription, and peptide-mediated synaptic stability in brain tissue. Activates interleukin-2 mRNA synthesis.

Research Summary

Evidence level: animal studies. Clinical status: Preclinical research; approved in Russia as supplement.

Side Effects & Safety

Important Warnings

  • Not FDA approved
Generally well-tolerated
limited safety data outside Russia

References

No references available.

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