Peptipedia
Growth HormoneIn Clinical TrialsClinical Trials

Hexarelin

Also known as Examorelin, HEX

A synthetic hexapeptide GH secretagogue with the strongest GH-releasing effect among GHRPs. Also has notable cardioprotective properties independent of GH release.

Investigational - Clinical trials conducted
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Regulatory Pathway

Preclinical
Phase I
Phase II
Phase III
Phase IV
Approved

Dosing Protocol

Typical Dose

100-200 mcg per injection

Frequency

2-3 times daily

Duration

4-8 weeks (desensitization occurs)

Community-reported dosing. Individual results vary. Not a medical recommendation.
Typical community protocol: 100-200 mcg per injection via Subcutaneous injection (fasted state required), 2-3 times daily. Dose range: 100-200 mcg per dose. Duration: 4-8 weeks (desensitization occurs).

Timing & Administration

Administer via Subcutaneous injection (fasted state required). Frequency: 2-3 times daily.

Mechanism of Action

Activates ghrelin receptors (GHSR-1a) causing potent GH release. Also binds to CD36 receptors in cardiac tissue, providing cardioprotective effects independent of GH. Causes significant cortisol and prolactin elevation.

Research Summary

Evidence level: clinical trials. Clinical status: Investigational - Clinical trials conducted.

Side Effects & Safety

Important Warnings

  • Receptor desensitization occurs with continuous use
Increased appetite
water retention
tingling/numbness
elevated cortisol and prolactin
flushing
headache
histamine release potential
receptor desensitization

References

No references available.

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