TB-500
Also known as Thymosin Beta-4 fragment
A synthetic 17-amino acid fragment of Thymosin Beta-4 with a longer half-life (~2-4 days) compared to the full protein (~2 hours).
Regulatory Pathway
Dosing Protocol
Typical Dose
2-2.5 mg twice weekly (loading), 2.5 mg once weekly (maintenance)
Frequency
2x weekly for 4-6 weeks, then 1x weekly
Duration
4-6 weeks loading, then maintenance
Timing & Administration
Administer via Subcutaneous or intramuscular injection. Frequency: 2x weekly for 4-6 weeks, then 1x weekly.
Popular Uses
Mechanism of Action
Promotes cell migration by binding to and sequestering actin. Upregulates actin expression, promotes angiogenesis, reduces inflammation, and facilitates hair follicle stem cell migration for wound healing.
Research Summary
Evidence level: animal studies. Clinical status: Preclinical - No human clinical trials, FDA Category 2 (restricted from compounding).
Side Effects & Safety
Important Warnings
- Contraindicated with active cancer or cancer history
- WADA prohibited
- May trigger histamine release.
References
No references available.
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